Literature Review

Evaluating the clinical reasoning of generative AI in palliative care: A comparison with five years of pharmacy learners Journal of Palliative Medicine; by Mikaila T Lane, Toluwalase A Ajayi, Kyle P Edmonds, Rabia S Atayee; 9/9/25Context: Artificial intelligence (AI), particularly large language models (LLMs), offers the potential to augment clinical decision-making, including in palliative care pharmacy, where personalized treatment and assessments are important. Conclusions: While LLMs [large language models] show potential for augmenting clinical decision-making, their limitations in patient-centered care highlight the necessity of human oversight and reinforce that they cannot replace human expertise in palliative care. This study was conducted in a controlled research setting, where LLMs were prompted to answer clinical reasoning questions despite default safety restrictions.