Literature Review

All posts tagged with “Clinical News | Pharmacy & Medication News.”



‘We don’t talk about death’: Winston-Salem journalist seeks to help people understand dying, deathbed visions

05/31/24 at 03:00 AM

‘We don’t talk about death’: Winston-Salem journalist seeks to help people understand dying, deathbed visions Fox 8 WGHP - High Point, NC; by Bob Buckley; 5/29/24 There may not be anything that fascinates people more than death. It may be the thing many people avoid confronting the most. “In our culture, we’re pretty separated from death. And I don’t know the figures, but the vast majority … take place in hospitals. We don’t talk about death a lot in our culture,” said Phoebe Zerwick, a journalist based in Winston-Salem who recently wrote about deathbed visions for the New York Times Magazine. ... Zerwick became aware of the work of Dr. Christopher Kerr. ... “The biggest difference between hallucinations and these experiences is how the person is made to feel,” Dr. Kerr said. “Most hallucinations leave the person distressed and agitated and would be further confused. These experiences bring comfort. They bring meaning. They’re drawn from life. They really validate the life.” ... “I think the moral of the story is to be present and to be present with people when they are terminally ill. Be present when they’re dying,” Zerwick said.

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Laws in motion to bring ‘Right to Try’ psychedelics at end-of-life

05/27/24 at 03:00 AM

Laws in motion to bring ‘Right to Try’ psychedelics at end-of-life Hospice News; by Holly Vossel; 5/21/24Hospice providers are navigating an evolving landscape of laws opening up pathways of access around psychedelic utilization at the end of life. Despite mounting evidence that psychedelics can improve experiences and reduce symptom burden in some terminally ill patients, these drugs remain difficult to access for those wishing to utilize them. Some states and the federal government have considered legislation that would establish a “right to try” psychedelics and other experimental interventions for certain seriously ill patients. 

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Nurse charged with stealing pills while taking care of hospice patient

05/27/24 at 03:00 AM

Nurse charged with stealing pills while taking care of hospice patient Fox56; by Emily Cherkauskas; 5/22/24Pennsylvania State Police say a registered nurse stole hundreds of prescription pills while taking care of a hospice patient. According to Pennsylvania State Police, on Feb. 12, troopers were contacted by the director of operations at the Amedisys Home Health / Hospice Care. Troopers were told that Registered Nurse Ashley Laura Miller, 36, of Mohrsville, had become a suspect in the theft and diversion of Oxycodone and Ativan prescriptions. ... [Upon] the passing of the patient, an additional nurse noted that 200 Oxycodone and 30 Ativan pills were missing from the narcotics count. ... On Wednesday, May 22, Miller was arraigned with bail set at $5000.

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Optum Rx puts emphasis on predictability with new pricing model

05/23/24 at 03:00 AM

Optum Rx puts emphasis on predictability with new pricing model Fierce Healthcare; by Paige Minemyer; 5/20/24 Optum Rx is rolling out a new pharmacy model that seeks to make drug costs more predictable and transparent for clients. The Optum Rx Clear Trend Guarantee aligns guarantees into single per member cost, encompassing retail, home delivery, specialty drug and rebate components in one guarantee. It provides an alternative to Optum's Cost Made Clear offering, which includes pass-through models and cost-plus pricing. ... Clear Trend Guarantee will be available on Jan. 1 alongside the existing Cost Made Clear program, Optum said.

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A Philadelphia pharmacy’s closure after 26 years highlights the industry’s growing challenges

05/14/24 at 03:15 AM

A Philadelphia pharmacy’s closure after 26 years highlights the industry’s growing challenges Times Daily; by Lizzy McClellan Ravitch, The Philadelphia Inquirerer; 5/11/24Last Monday, Friendly Pharmacy filled 318 prescriptions. For about 100 of them, insurance companies paid the pharmacy less than $3. In 22 instances that day, the reimbursement was less than the cost of the medication. ... [Managing pharmacist Brad] Tabaac plans to close his doors on May 31 after 26 years in business. ... Independent pharmacies like Friendly, as well as some chains, have been pinched by pricing and fees set by pharmacy benefit managers — the companies that handle prescription drug plans for health insurance. The three biggest pharmacy benefit managers are CVS Health, Optum Rx and Express Scripts. They control nearly 90% of the market, according to the National Community Pharmacists Association (NCPA), and some of their parent companies also own pharmacies.

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A narrative review of risk mitigation strategies in the management of opioids for chronic pain and palliative care in older adults: Interprofessional collaboration with the pharmacist

05/14/24 at 03:00 AM

A narrative review of risk mitigation strategies in the management of opioids for chronic pain and palliative care in older adults: interprofessional collaboration with the pharmacist Annals of Palliative Medicine; by Insaf Mohammad, Candice L Garwood, Lisa Binns-Emerick Key content and findings: A variety of risk mitigation strategies to improve safety for older adults using opioids exist. They include risk assessment, tapering opioids, reducing high-risk concomitant medications, utilizing non-opioid therapies, screening for and treatment of opioid use disorder (OUD), toxicology testing, co-prescribing naloxone, utilizing controlled substance agreements, reviewing prescription drug monitoring program data, prescriber and patient education, and collaboration with pharmacists and palliative care specialists.

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Opioid manufacturer Endo Health Solutions Inc. ordered to pay $1.536B in criminal fines and forfeiture for distributing misbranded opioid medication

05/09/24 at 03:00 AM

Ordered to pay $1.536B in criminal fines and forfeiture for distributing misbranded opioid medication Office of Public Affairs, U.S. Department of Justice; Press Release; 5/3/24Endo Health Solutions Inc. (EHSI) was ordered to pay $1.086 billion in criminal fines and an additional $450 million in criminal forfeiture — the second-largest set of criminal financial penalties ever levied against a pharmaceutical company —for violations of the Federal Food, Drug and Cosmetic Act related to the distribution of the opioid medication Opana ER with INTAC (Opana ER). ...

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Association between opioid use disorder and palliative care: a cohort study using linked health administrative data in Ontario, Canada

05/04/24 at 02:55 AM

Association between opioid use disorder and palliative care: a cohort study using linked health administrative data in Ontario, CanadaCMAJ; by Jenny Lau, Mary M. Scott, Karl Everett, Tara Gomes, Peter Tanuseputro, Sheila Jennings, Rebecca Bagnarol, Camilla Zimmermann and Sarina R. Isenbergl; 4/29/24Background: People with opioid use disorder (OUD) are at risk of premature death and can benefit from palliative care. We sought to compare palliative care provision for decedents with and without OUD.Conclusion: We identified important differences in palliative care provided at the end of life between people with and without OUD. People with OUD were less likely to receive palliative care despite accessing palliative care earlier, which may reflect their end-of-life illness trajectories and underlying structural vulnerability that may prompt them to receive palliative care primarily in acute care. Health care providers should receive training in palliative care and addiction medicine to support people with OUD. 

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Substance use disorders in hospice palliative care: A narrative review of challenges and a case for physician intervention

05/04/24 at 02:45 AM

Substance use disorders in hospice palliative care: A narrative review of challenges and a case for physician interventionCambridge University Press; by Lauren Rudy and Emilie Lacroix; 2/29/24Objectives: Substance use disorders (SUDs) are frequently encountered in hospice palliative care (HPC) and pose substantial quality-of-life issues for patients. However, most HPC physicians do not directly treat their patients’ SUDs due to several institutional and personal barriers. ...Results: ... Recommendations for physicians and training environments to address these challenges include developing familiarity with standardized SUD assessment tools and pain management practice guidelines, creating and disseminating visual campaigns to combat stigma, including SUD assessment and intervention as fellowship competencies, and obtaining additional training in psychosocial interventions.

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Deciphera Pharmaceuticals to be acquired by Ono Pharmaceutical for $2.4 billion

05/02/24 at 03:00 AM

Deciphera Pharmaceuticals to be acquired by Ono Pharmaceutical for $2.4 billion LevinPro HC; 4/30/24Deciphera Pharmaceuticals announced on April 29 that it has entered into a definitive merger agreement with Ono Pharmaceutical Co., Ltd. to be acquired for a total equity value of $2.4 billion. Upon completion, Deciphera will operate as a standalone business of Ono, from its headquarters in Waltham, Massachusetts. 

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Walmart Health is closing

05/02/24 at 02:00 AM

Walmart Health is closingWalmart; 4/30/24Back in 2019, we launched Walmart Health centers. During our five-year journey, we made meaningful impacts with patients while continuing to learn, pivot and evolve. While our mission to help people save money and live better remains, today we are sharing the difficult decision to close Walmart Health and Walmart Health Virtual Care. Through our experience managing Walmart Health centers and Walmart Health Virtual Care, we determined there is not a sustainable business model for us to continue.

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Drug discount program is exploiting poor patients while corporate giants profit

04/30/24 at 03:00 AM

Drug discount program is exploiting poor patients while corporate giants profit Minnesota Reformer; by David Balto; 4/26/24 ... The federal 340B drug discount program was created three decades ago to help economically vulnerable Americans access affordable prescription medications and providers in underserved areas expand and improve services. Under the program, drug companies participating in Medicaid — known in Minnesota as Medical Assistance — provide sizeable discounts as high as 50% to these ‘safety net’ health care facilities. ... Unfortunately, over time, the tens of billions of dollars flowing through this program have proven irresistible to for-profit corporate entities, including giant health systems and big box chain pharmacies — and there is no guarantee those discounts are reaching patients. 

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Attitudes and beliefs regarding Pain Medicine: results of a national palliative physician survey

04/30/24 at 03:00 AM

Attitudes and beliefs regarding Pain Medicine: results of a national palliative physician survey Journal of Pain and Symptom Management; by Daniel K Partain, Wil L Santivasi, Mihir M Kamdar, Susan M Moeschler, Jon C Tilburt, Karen M Fischer, Jacob J Strand; 4/25/24 online ahead of print Objectives: To evaluate referral rates, co-management strategies, and beliefs of palliative physicians about the value of Pain Medicine specialists in patients with serious illness. Conclusion: This study shows that Palliative Care physicians have highly positive attitudes toward Pain Medicine specialists, but referrals remain low. Facilitating professional collaboration via joint educational/clinical sessions is one possible solution to drive ongoing interprofessional care in patients with complex pain.

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The Dos and Don’ts of enhanced service contracts

04/29/24 at 02:00 AM

The Dos and Don’ts of enhanced service contractsSpecialty Pharmacy Continuum; by Marcus A. Banks; 4/25/24 ... Any pharmacy that interacts with patients—an independent pharmacy, an ambulatory infusion clinic, a health system or specialty pharmacy—can enter an enhanced service contract with a pharmaceutical company. All services offered under these contracts should be documented, auditable and offered at fair prices. Before approaching the company about partnering, Mr. Suchanek advised understanding the distinction between basic and enhanced services. ... “Pharmacy leaders need to demonstrate that they are credible partners,” [David] Suchanek said [Executive Vice President for  Biotech & Specialty Services at D2 Solutions].

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AI could play role in preventing prescribing of unnecessary drugs in older adults

04/26/24 at 03:00 AM

AI could play role in preventing prescribing of unnecessary drugs in older adults McKnights Senior Living, by Kristen Fischer; 4/22/24 A new study finds that artificial intelligence could encourage doctors to stop prescribing drugs that aren’t necessary — especially in older adults, who tend to be on multiple medications. The report was published 4/18 in the Journal of Medical Systems. More than 40% of older adults are taking five or more prescription medications, a rate that raises their risk for potentially harmful drug interactions. ... AI isn’t a perfect tool compared with having an actual doctor. For instance, it tended not to pay much attention to a person’s pain level, suggesting that the patient stop taking pain medications but not others for clinical ailments such as high cholesterol or high blood pressure, the authors reported.

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Cardinal Health, OptumRx break up

04/26/24 at 03:00 AM

Cardinal Health, OptumRx break up Becker's Hospital Review, by Paige Twenter; 4/22/24Cardinal Health's pharmaceutical distribution contracts with OptumRx, a subsidiary of UnitedHealth Group, will not be renewed, the medical distributor said April 22.  The contracts, which mainly included non-specialty bulk shipments to Optum's mail dispensing sites, will expire in late June. In 2023, sales to OptumRx generated 16% of Cardinal Health's consolidated revenue. "Total sales to OptumRx generate a meaningfully lower operating margin than the overall pharmaceutical and specialty solutions segment," Cardinal said. McKesson Corp. won the contract, according to Bloomberg, which cited Evercore ISI. 

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Comparative effectiveness of acupuncture vs massage for relieving pain in patients with advanced cancer

04/19/24 at 03:00 AM

Comparative effectiveness of acupuncture vs massage for relieving pain in patients with advanced cancer The ASCO Post; by Jun J. Mao, MD, MSCE and Andrew S. Epstein, MD; 4/17/24... The IMPACT study was conducted at Memorial Sloan Kettering Cancer Center and regional sites in New York, New Jersey, and Florida to evaluate the long-term comparative effectiveness of acupuncture vs massage for pain in patients with advanced cancer. ... The primary outcome—change in worst pain intensity score from baseline to 26 weeks—was measured using the Brief Pain Inventory (BPI ranging from 0–10; higher numbers indicate worse pain intensity or interference). The secondary outcomes included fatigue, insomnia, and quality of life. ... To use these therapies, it is important to seek credentialed practitioners who have training or experience in working with patients who have cancer. 

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Governor Lamont annnounces $35.5 million in state grants to support nonprofit providers with capital improvement projects [$775 thousand to Connecticut Hospice]

04/12/24 at 03:00 AM

Governor Lamont announces $35.5 million in state grants to support nonprofit providers with capital improvement projects [$775 thousand to Connecticut Hospice]  State of Connecticut, Office of the Governor; 4/10/24 Governor Ned Lamont today announced that his administration is awarding approximately $35.5 million in state funding to nonprofit providers across Connecticut for capital improvement projects that support each respective organization in their mission of delivering services to some of the state’s most vulnerable residents. The grants are being released through the state’s Nonprofit Grant Program, which is administered by the Connecticut Office of Policy and Management. [The list includes:] ... "Branford – Connecticut Hospice: $775,000 (Pharmacy Improvements)"

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‘We’re the telescope looking forward’: Medical ethicists ask tough questions as part of $66 million research project

04/09/24 at 03:00 AM

‘We’re the telescope looking forward’: Medical ethicists ask tough questions as part of $66 million research project CU Department of Medicine, by Mark Harden; 4/5/24 In the original “Jurassic Park” movie, after the process of bringing dinosaurs back to life is explained to a team of consultants, one of them voices a warning: “Your scientists were so preoccupied with whether or not they could, they didn’t stop to think if they should.” University of Colorado Department of Medicine faculty members will be asking the “should” question years before there’s an answer to “could.” They’ve joined in a nationwide study of whether tiny, battery-powered electric devices and genetic material, swallowed in capsule form, could one day replace surgery or injections as treatments for metabolic diseases such as diabetes and obesity.

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Chicago area nurse gets 2 years in prison for stealing morphine from sick patients

04/08/24 at 03:00 AM

Chicago area nurse gets 2 years in prison for stealing morphine from sick patientsCBS News TV 2, Chicago; by Acacia Hernandez; 4/4/24A northwest suburban nurse was sentenced in court on Thursday to two years in federal prison for stealing morphine from her patients, some of whom were terminally ill. Sarah Diamond, 31, of Woodstock, was accused of targeting the most vulnerable, including hospice patients living out their final days. In 2021, she removed liquid morphine from bottles that had been prescribed to at least five hospice patients and replaced it with saline. Prosecutors said she took the medication for her own personal use.

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Cancer patients often want ‘one more round.’ Should doctors say no?

04/02/24 at 03:00 AM

Cancer patients often want ‘one more round.’ Should doctors say no? The Washington Post, by Mikkael A. Sekeres, MD; 3/31/24 My patient was in his early 30s and his leukemia had returned again following yet another round of treatment. He was a poster child for the recently reported rise in cancer rates in the young, and had just asked me what chemotherapy cocktail I could devise for him next, to try to rid him of his cancer. I hesitated before answering. Oncologists are notorious for always being willing to recommend to our patients one more course of treatment, even when the chances of success are negligible.  

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Expanding the use of continuous sedation until death and physician-assisted suicide

03/29/24 at 03:00 AM

Expanding the use of continuous sedation until death and physician-assisted suicide  The Journal of Medicine & Philosophy: A Forum for Bioethics and Philosophy of Medicine; by Samuel H Lipuma and Joesph P Demarco; 3/27/24 The controversy over the equivalence of continuous sedation until death (CSD) and physician-assisted suicide/euthanasia (PAS/E) provides an opportunity to focus on a significant extended use of CSD. 

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Antibiotics in end-of-life care

03/29/24 at 03:00 AM

Antibiotics in end-of-life care NEJM Journal Watch, by Abigail Zuger, MD; 3/27/24Antibiotics often are considered to be among the gentler and more comfort-oriented interventions in end-of-life care, certainly far less aggressive than intubation or last-ditch surgery. ... Still, antibiotics do entail their own costs in the form of toxicities and need for intravenous access, and liberal antibiotic use reliably worsens institutional and community drug-resistance profiles. ... A new review was written for infectious disease consultants but contains specific suggestions that should interest both generalists and other subspecialists caring for dying patients. 

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Nurse arrested after morphine, other stolen medical drugs seized in Owensboro

03/28/24 at 03:00 AM

Nurse arrested after morphine, other stolen medical drugs seized in Owensboro14 News WFIE, by Aaron Chatman; 3/26/24 Eight suspects were arrested and facing numerous charges after a massive drug bust in Owensboro. That’s according to the Daviess County Sheriff’s Office, who says they opened an investigation after receiving dozens of tips about a drug trafficking operation at the home of Pamela Bartimus. Deputies say Bartimus was an employee of Hospice & Palliative Care of Western Kentucky and had been stealing medication at her job.

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Partners In Care sets sights on service diversification, hospice-pharmacy partnership

03/26/24 at 03:00 AM

Partners In Care sets sights on service diversification, hospice-pharmacy partnership Hospice News, by Jim Parker; 3/22/24 Hospice providers need to evolve with their changing patient populations and the larger health care system, according to Greg Hagfors, CEO of Partners In Care. The Oregon-based hospice, palliative care and home health provider recently celebrated the 45th anniversary of its founding, which preceded the establishment of the Medicare Hospice Benefit. ... Hospice News recently spoke with Hagfors about the ways the industry has changed since Partners In Care came on the scene — and how it is moving towards the future.

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